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Mueller RS et al
A defective gut mucosal barrier may result from the loss of butyrate-producing bacteria, allowing the passive leakage of microbial toxins such as LPS, which bind to TLRs and other innate immune system receptors, triggering inflammation (Furusawa et al., 2013)
[DOI] [PubMed] [Google Scholar] 63.Wu C., Zhu M., Lu Z., et al
CBT helps patients recontextualize pain and discomfort, thereby changing the brains physiological response to pain
