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Description
The reason for the model selection was the fact that livers are highly populated with human hepatocytes and that the major human drug metabolizing enzymes (including UGT1A9 - the enzyme of interest) and transporters are active in the liver.
Glutathione (98%) Brightens and reduces hyperpigmentation
Concanavalin A (Con A)-induced hepatitis model is well-established experimental T cell-mediated liver disease
Oliveira DR1, Todo AH2, Rgo GM3, Cerutti JM4, Cavalheiro AJ5, Rando DGG2, Cerutti SM6
