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Vitamin B12 plays a pivotal role in supporting numerous bodily functions, ensuring you perform at your best both mentally and physically

Moreover, ROS can directly damage the ETC, oxidizing its protein constituents and decreasing its efficiency, thereby increasing electron leakage and ROS generation

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Beyond pathway inhibition, polyphenols modulate immune responses by influencing macrophage and microglial polarization, shifting from a proinflammatory M1 phenotype to an antiinflammatory M2 state, thereby enhancing the release of antiinflammatory mediators such as IL10 and arginase1 (Di Meo et al