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10.1016/j.jhazmat.2020.123020 33 KazanK.MannersJ
Key points Abdominal pain in chronic constipation (FC/IBS-C) stems from fecal/gas distension, gut dysbiosis (e.g., histamineproducing bacteria), serotonin imbalances (linked to IBS-C pain), and neural dysfunction (central/peripheral sensitization)
Julius, M., Lang, C
