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Expression of system xc activity by transfection with cDNAs for xCT and 4F2hc made A2780 cells more resistant to CDDP
FOXO4-DRI is a cell-permeable senolytic peptide antagonist for inducing apoptosis in senescent cells in aging and apoptosis research from APExBIO.
The peptide's exceptional selectivity for senescent cells, combined with its well-characterized mechanism of FOXO4-p53 interaction disruption, provides researchers with powerful capabilities for investigating senescence biology that were previously impossible to study
