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Other factors also impair estrogen clearance: liver congestion, gut microbiome composition (bacteria that produce beta-glucuronidase can reactivate excreted estrogen), cortisol (which shifts the livers priorities away from estrogen clearance), and alcohol use (which directly competes for liver detox capacity) [7]
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K.WiltbankM

Pulsed dye laser treatment of rosacea improves erythema, symptomatology, and quality of life

doi: 10.1073/pnas.1009152108
