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3.4 The impact of CR disruption on IVD Chronic disruption of internal CRs, along with daily metabolic needs, can lead to cumulative stress and imbalances within the body, potentially contributing to the early onset of age-related diseases (Neves et al., 2022)

Pigmentation & Skin-Integrity Research Research involving Glutathione commonly investigates its interaction with: Tyrosinase-related mechanisms Melanin-related signaling pathways Oxidative-stress regulation within melanocyte research models Skin-integrity and dermal-maintenance pathways These pathways have contributed to broader research interest in Glutathione within pigmentation-related, dermatological, cosmetic, and skin-quality investigations

Pradedova, E.V

Heterogeneous data addressing both perspectives can be found in the literature