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Description
Firstly, long-chain fatty acids are converted to long-chain acyl-CoA catalyzed by acyl-CoA synthetases in the endoplasmic reticulum and outer mitochondrial membrane

Bussel J, et al

As we all know, Macrophage-induced inflammation promotes the differentiation of CD4 T cells into Th17 cells, which inhibits Treg cell function

Journal of Neurosurgery: Pediatrics 2012;9(6):621-626
