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The same metabolic dysfunction that characterizes endometriosis appears in varying degrees across Hashimoto thyroiditis and other conditions where chronic inflammation drives tissue damage

The tendency reported in the different studies is not always consistent, increasing in some studies, while decreasing in others

It remains unclear whether different iPSC lines differ in their capacity to engage with the host environment, particularly in terms of glial reactivity or recruitment of myelination, and what the donor-specific factors that shape the differential graft outcomes are

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