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By approximately Day 45, the participant described: improved overhead movement reduced radiating pain lower baseline pain intensity from 8/10 VAS to 6/10 VAS restored work capacity while still emphasizing incomplete recovery

2004 Mar;134(3):489-92

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For instance, studies demonstrate distinct gene expression patterns and immune cell infiltrates between eutopic and ectopic tissues, and across lesion locations, suggesting variable responsiveness to immunomodulatory or microbiome-targeted therapies ( Future therapeutic frameworks should thus integrate phenotypic, molecular, and patient-specific factors to guide individualized treatment