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In contrast, IRP2 knockdown or treatment with the ferroptosis inhibitor Fer-1 alleviates PC-12 cell damage by downregulating p53 levels and activating the SLC7A11-ALOX12 signaling pathway (Yao et al., 2024)

10.2214/AJR.15.15842 94 SemelkaR

GSH, as an important ferroptosis suppressor and non-enzymatic antioxidant, provides a vital defense system to protect cells from different types of oxidative stress [29]