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These changes occurred before the increase in THDA levels, indicating that the loss of BDNF-TrkB signalling and upregulation of GSTO2 happens before the hyperdopaminergic state, as with the Trkb Penk -KO mice, supporting that GSTO2 increase is more likely a cause of neurodegeneration than a consequence of it
Illustratively, the compression force of 6066 g used produced a severe injury [1,109], and all of the therapy effects may provide relevant information for the human disturbances as well
Guler et al., 2021)
Ranibizumab (Lucentis)
