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This milestone study was crucial for understanding the relationship between Zot and zonulin, demonstrated an NH 2 -terminus receptor-binding motif shared between Zot and zonulin, and provided the foundational peptide drug now being studied in phase III clinical trials for adult patients with celiac disease

Nonetheless, there is insufficient direct evidence to elucidate the relationship between Klotho protein and markers of inflammation and apoptosis in OSAHS patients