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Research indicates that AOD-9604 may act, at least in part, through beta-3 adrenergic receptor (3-AR) signaling a pathway tightly associated with fat oxidation in visceral and brown adipose tissue
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Arpaia N, Green JA, Moltedo B, Arvey A, Hemmers S, Yuan S, et al
3B), induce the recruitment of immune inflammatory cells, NO production, foam cell formation, enhance mitochondrial ROS production, and Mphs secretion of cytokines, such as TNF, IL-12p70, IL-6, IL-10, IFN [114]
