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After this filtering, RMA-tracing candidate peaks were found by searching for their cysteine labelled m + 4 isotopologue peaks using a maximum difference between theoretical and observed exact mass of 10 ppm, a maximum retention time difference of 0.25 min and a labelling fraction range of 0.20.28 or 0.340.42 observed in at least one sample

doi: 10.3389/fpsyt.2018.00655, Summary Keywords astrocytes, disease, homeostasis, metabolism, microglia, neurons Citation Pang Y, Yang J, Liu J, Xie Z and Wang J (2026) Metabolic interactions in the brain: the crucial roles of neurons, astrocytes, and microglia in health and disease

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Next, we will explore how these circulating metabolites disrupt intrapulmonary metabolic homeostasis, thereby directly linking systemic metabolic dysregulation to local pulmonary pathology