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Aguiar AS, Duzzioni M, Remor AP, Tristo FSM, Matheus FC, Raisman-Vozari R, Latini A, Prediger RD

GPX4KO CAOV3 cells resuspended in PBS exhibited markedly impaired intraperitoneal growth compared with WT cells, whereas GPX4KO cells resuspended in ascites displayed tumor growth comparable to WT cells, demonstrating that ascites directly suppresses ferroptosis in vivo (Fig

doi: 10.1021/ac101022m

In HCECs applied with desiccating stress, the CEC ferroptosis was triggered by the aggregation of autophagy impairment-derived sequestosome 1 (SQSTM1), the overexpression of which fostered ferroptotic changes and substantially elevated ACSL4 (124)