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The linear mixed-effects model (LMM) was constructed to account for both fixed and random effects, ensuring a robust analysis of the longitudinal data, so we applied LMM to analyze the longitudinal outcome variables including instrument scores (for patients 37 and 920) and LPP substrate amplitudes (for patients 1120), for which the model included fixed effects for relapse status and time (different time points [TPs], defined in Supplementary Methods 3.8 and 9.3) and a random effect of patient ID

Injection Sites and Technique Preferred sites: Lower abdomen (at least two inches from the navel), outer thigh, upper arm fat pad

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This syndet bar is also formulated with nourishing ingredients to gently cleanse the skin without drying it out, maintain the skin's natural moisture barrier, and preserve skin's protective oils leaving skin feeling soft and clean