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Nieman DC, Dumke CL, Henson DA, McAnulty SR, Gross SJ, Lind RH
By encapsulating drug molecules in nanoparticles, nanoparticle drug delivery systems exhibit the advantage of improved drug loading, less exposure of the drug molecule to metabolic enzymes and drug efflux pumps, longer blood circulation, and facilitation of drug passage through the cell membrane via transcytosis instead of passive diffusion
