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This is especially true if the marketing targets underage users
While 12 weeks of bright light exposure did not produce measurable improvements in sleep quality, glucose metabolism, or inflammatory markers, it significantly altered clock gene expression in peripheral blood mononuclear cells (PBMCs, specifically decreasing REV-ERB levels and increasing the REV-ERB/BMAL1 ratio)
807,808 However, off-target effects and genotoxicity remain significant concerns in the therapeutic use of CRISPR-Cas9
In contrast, for lighter smokers, the effect might be inverse, potentially due to a thicker layer of mucus (58, 60)
