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Melanosome Transport and Autophagy Melanosome trafficking from the perinuclear area of melanocytes to peripheral dendrites, where pigments are transferred to keratinocytes, is tightly regulated by cytoskeleton-linked motor proteins, such as kinesin, the tripartite protein complex Rab27a/melanophilin/myosinVa, and small GTP-binding proteins [124]

Supplementation with Bifidobacterium longum Bar33 and Lactobacillus helveticus Bar13 mixture improves immunity in elderly humans (over 75 years) and aged mice

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and (3) even molecularly identical tumors may have highly variable responses to the same drug