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2.5.2 Acylation of the Spike protein Palmitoylation is vital for coronavirus infectivity, at least in part because of the S-acylation of Spike ( Spike proteins from several coronaviruses are heavily palmitoylated in cysteine residues, e.g., SARS-CoV-2 Spike is palmitoylated in 10 cytosolic residues (181183)
