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CD39 and CD73 are ectonucleotidases that sequentially hydrolyze extracellular ATP to adenosine, an immunosuppressive metabolite

The relatively high expression of neuroglobin in the central and peripheral nervous systems [at near micromolar protein levels (246)] suggests that it plays a role in controlling blood perfusion, redox regulation, O 2 levels, and NO signaling in vascular coupling to the nervous system

Genotyping was performed by The Wellcome Trust Sanger Institute, support of the National Eye Institute via an NIH/CIDR genotyping project
