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In the human prostate, both 5 -reductase isozymes are present in epithelial cells and stromal cells, while 5 -reductase-2 is the predominant isozyme expressed in the stromal cells 14 , 20 , 23
J Biol Chem 2008;281:898190
4d, e, g) and a decrease in intracellular protection against ROS-like glutathione activity (Fig
