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It also induced apoptosis through the mitochondrial pathway, increasing Bax/Bcl-2 ratio and activating caspase-9 and caspase-3

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Souto EB, Cano A, Martins-Gomes C, Coutinho TE, Zieliska A, Silva AM

Secondly, its cross-sectional design precludes the observation of longitudinal changes in Type 2 biomarkers
