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Regulation of pituitary GH secretion In 1985, Plotsky and Vale demonstrated in rats that the episodic secretion of GH was under a dual hypothalamic control exerted by growth hormone-releasing hormone (GHRH) and somatostatin (SS) [7]

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Nuclei were stained with DAPI and anti- -H2AX antibody was used to mark double-strand breaks sites

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