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Mitochondria are highly vulnerable to copper-mediated injury, leading to oxidative damage to their membranes ( Copper serves as a cofactor for various mitochondrial enzymes involved in ATP production, a process that relies on the TCA cycle and OXPHOS within mitochondria (Sheline and Choi, 2004

Conclusion We investigated OM of mono- and di-unsaturated phospholipids in solution and for the first time also on liposomes with the 2nd generation Hoveyda-Grubbs catalyst ( HGII ) and two derivatives, a water soluble PEGylated HGII ( C3 ) and a palmitoylated HGII derivative ( C4 )

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Experimental evidence demonstrated that stromal interaction molecule 1 (STIM1) expression was significantly downregulated in cortical neurons of mice with experimental autoimmune encephalomyelitis (EAE) induced by MOG35-55