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For apoptosis, PI3K/Akt is a key pathway, with the main members are phosphatidylinositol 3-kinase (PI3K) and protein kinase B (Akt)

In SARS-CoV-2 infected patients, the plasma levels of ferritin and IL-6 steadily decrease with gradual recovery from COVID-19 152,153

As compared to control cells, the NADPH levels and the GSH/GSSG ratio were significantly decreased, whereas mitochondrial ROS and intracellular H 2 O 2 levels were increased in GDH1 knockdown cells [67]

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