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The GSH and NAC digestive degradation occurring during oral treatments lead to consider GSH and NAC nebulization as a viable alternative to manage early stages of COVID-19 disease (Santos Duarte Lana et al., 2021)

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Lipoylation is an essential mitochondrial modification arising from conjugation of lipoic acid (lipoate), a redox-sensitive fatty acid, to lysine residues (K Lp ) 13,14