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Loss of the serine/threonine kinase PINK1 results in mitochondrial dysfunction and activates the cGAS-STING pathway, ultimately leading to renal aging-related phenotypes [306]

CrossRef Gut microbiota: The key to the treatment of metabolic syndrome in traditional Chinese medicine a case study of diabetes and nonalcoholic fatty liver disease Yang Bao, Xiao Han, Da Liu, Zhaolin Tan, Yongzhi Deng Frontiers in Immunology .2022;[Epub] CrossRef DPP-4 Inhibitor in Type 2 Diabetes Mellitus Patient with Non-Alcoholic Fatty Liver Disease: Achieving Two Goals at Once

The ultimate therapeutic dose should be achieved on the basis of both tolerability and clinical response (see Use in the Elderly under Precautions and Pharmacology: Pharmacokinetics: Special Populations: Geriatric under Actions)

Am J Cardiovasc Drugs
