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Knoop 5 1 Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia, 2 Department of Maternal, Newborn, Child, Adolescent Health and Ageing, World Health Organization, Geneva, Switzerland, 3 Department of Rehabilitation Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium, 4 Geriatrics Section, Department of Internal Medicine, University of Palermo, Palermo, Italy, 5 Department of Gerontology, Vrije Universiteit Brussel (VUB), Brussels, Belgium