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Additionally, both AMPK and ULK1 can phosphorylate Atg9, a transmembrane protein involved in the early formation of autophagosomes, thereby exerting control over its localization

Building on this potential, to advance the clinical translation of MR, we propose the following key directions: First, achieving precise patient selection-given the heightened sensitivity of MTAP-deficient cancers to MR, MTAP status should be evaluated as a predictive biomarker to prioritize potential beneficiaries
Ferroptosis contributes to OA through several mechanisms: 1) Iron overload and lipid peroxidation: elevated iron levels in OA tissues lead to increased lipid peroxidation, which damages cell membranes and induces cell death

Additionally, the cooking process and digestion significantly reduce the amount your body absorbs, making supplements a more practical choice for reaching skin-specific targets
