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The molecule corresponds to an amino acid sequence comprising positions 176-191 in the structure of hGH and is described in the literature as a fragment associated with the lipolytic domain of growth hormone

Elevated cAMP activates protein kinase A (PKA), which then phosphorylates and activates hormone-sensitive lipase (HSL)

Histology may reveal epidermal thinning, vacuolar changes and nuclear elongation of keratinocytes, increases in the number of melanocytes in basal layers, and the presence of numerous melanophages in the papillary dermis.3,9 Electron microscopy will show intracytoplasmic desmosomes, numerous aggregated bundles of tonofilaments in the cytoplasm of keratinocytes, and highly condensed keratohyalin granules.10 In the present case, the results of the 2 histological studies carried out were not consistent with the findings described above and were, rather, indicative of an adverse drug reaction