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For these experiments, we used silica-coated iron oxide nanoparticles (IONPs) that were synthesized from EMG308 iron oxide core nanoparticles (Ferrotec, Santa Clara, California) that were coated with a silica shell and surface modified with polyethylene glycol and a small hydrophobic ligand, trimethylsilane 22 , suspended in CPA (VMP), and filtered before use

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Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1