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Description
Limitations of the Efficacy of C-Met Inhibitors A large number of clinical trials have proved that the safety of HGF or c-Met inhibitors is reliable

In the earlier Phase 2 trial, the highest dose tested (45 mg) produced 14.7% weight loss at 36 weeks, suggesting that longer treatment and dose optimization may yield further improvements

2009;12:c184c189
Epub 2020 Feb 22
