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As of 2025, AOD-9604 should be regarded as a discontinued research peptide, not a therapeutic agent , with ongoing relevance confined to academic and mechanistic exploration

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With respect to DNA damage, it has been shown that iodine oxidizes 2-deoxy-8-oxoguanosine [164] and 8-oxo-7,8-dihydroguanine [165], both resulting from oxidative damage to guanine bases

10.1021/ja030396p J
