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The TH gene is located on chromosome 11p15.5 and is composed of 14 exons that generate three alternatively spliced mRNAs that encode tyrosine hydroxylase isoform a (528 amino acids), isoform b (497 amino acids), and isoform c (524 amino acids)

Forscher beschreiben eine Interaktion mit dem NO-System, die in Tiermodellen mit angiogenetischen Prozessen assoziiert wird

A meta-analysis has shown that the total concentration of SCFAs is significantly reduced in UC patients compared to healthy subjects, with decreased concentrations of acetic and propionic acids in patients with active UC

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