glutathione assay abcam Reduced (GSH) Colorimetric Kit and the maintenance of protein sulfhydryl groups in their reduced state Assay Kits

doi: 10.1152/physrev.00042.2016, [DOI] [PMC free article] [PubMed] [Google Scholar] Vervust W., Safaei S., Witschas K., Leybaert L., Ghysels A

Haddad M, Herve V, Ben Khedher MR, Rabanel JM, Ramassamy C

Learn more about genetic testing for Autoimmune diseases

With a goal of covering multiple biological systems to study effects on oxidation, the following models have been considered worth pursuing: Wild-type and mutant human GPX4 recombinant protein (available now at Karolinska Institute) CRISPR-edited GPX4 variant in reference cell lines (available now at Colombia University) SSMD patient-derived fibroblasts (available now at RUCDR Biorepository) SSMD patient-derived iPSC lines (available now at RUCDR Biorepository) Brain organoids derived from patient-derived iPSCs (not yet started) GPX4 conditional/complete knock-out mice (available now at JAX, Stock #027964) GPX4 condition knock-in mice (in-progress, ETA 1-Feb-2021) For genetic conditions, animal models are built by recreating the genetic variation in the animals genome or silencing the gene entirely