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Description
MC1R is a GPCR with seven -helical transmembrane (TM) domains, an N-linked glycosylation site at the external N-terminus, a palmitoylation site at the intracellular C-terminus, and a DRY motif at the junction of the third TM domain
Some specific attributes of these variants can be more easily recognized with digital dermatoscopy, facilitating early detection and possibly avoiding invasive procedures
Melanotan II subsequently became a frequently referenced peptide compound within experimental research focused on melanocortin receptor systems and molecular signalling pathways
N Engl J Med 348: 25992608, 2003
