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In addition to their metabolic enzyme functions, the PFK and PFKFB proteins are involved in the regulation of apoptosis and DNA repair

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10.1161/JAHA.120.018403 157

Recently, a study on a novel DDAH1 knockout (DDAH1 / ) rat strain model found DDAH1 dysfunction to significantly worsen RVSP and RVHI in DDAH1 / MCT model compared to the wild type MCT model (Wang et al., 2019)
