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Description
The continuous turnover of synovial fluid leads to a short residence time for the administered peptides in the joint space, whereas the dense, negatively charged cartilage matrix impedes their diffusive transport
Therefore, supplementing with methylcobalamin is the best option

doi: 10.1331/JAPhA.2008.07055 [DOI] [PubMed] [Google Scholar]

Proper technique maintains peptide integrity and ensures accurate dosing
