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Description
Hum Mutat 31: 809819
Quercetin reduced blood pressure by activating Na + -K + -2Cl cotransporter 1 (NKCC1) in renal epithelial cells, elevating cytosolic Cl concentration ([Cl ] c ) and downregulating gene expression of epithelial Na + channel (ENaC) [100,101]
Resveratrol ameliorates methotrexate-induced hepatotoxicity in rats via inhibition of lipid peroxidation
Ferroptosis also activates the cGAS-STING pathway, sustaining tumor-associated macrophage (TAM) recruitment and amplifying inflammatory signaling [129]
