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GSH was measured by adding the standard or sample to 100 L of a 1:1 mixture of 3 units/mL glutathione reductase with 0.67 mg/mL 5,5'-Dithiobis(2-nitrobenzoic acid) (DTNB)
The type II form represents about 5% of all cases of CGD and is the result of mutations in the NFC2 gene which encodes the p67-PHOX protein
These medications should be avoided by people who are pregnant or breastfeeding, those with a history of pancreatitis, and anyone with a personal or family history of medullary thyroid cancer or MEN2 syndrome
