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Nutrients 2022

When the FDA places a peptide in a restricted or high-risk category [known as Category 2], it is explicitly signaling that it has identified safety concerns and that enforcement discretion does not apply. But, as Hajduczok notes, just because something is not FDA-approved doesnt mean its illegal to compound, but the restricted peptides should not be compounded

During the ischemic phase, the deprivation of oxygen and essential nutrients leads to profound cellular dysfunction, metabolic disturbances, and potential structural damage [2]
