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Description
High-altitude illnesses: old stories and new insights into the pathophysiology, treatment and prevention
Butyrate acts blocks the IL-6/STAT3/IL-17 and TLR2-MyD88-NF-B pathways, and bidirectionally regulates cytokine secretion, Specifically, it upregulates anti-inflammatory factors such as IL-4 and IL-10 and downregulates pro-inflammatory factors such as CRP, IL-8, IL-12, and TNF- ( Meanwhile, butyrate also targets intestinal epithelial cells via EGFR-STAT3 and Nrf2 pathways
All images were taken with a 60 oil objective
Omelko and C
