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Additionally, a weight loss of more than 25% was achieved in 40.4% of patients receiving CagriSema, compared to 16.2% of patients receiving semaglutide 2.4 mg, 6% of patients receiving cagrilintide 2.4 mg and 0.9% of patients receiving placebo

The method of any one of claims 1 to 6, wherein the maleimide is N-ethyl-maleimide (NEM) and the heavy isotopologue of the maleimide is d5-NEM