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(2008) 90(4 Suppl.):13339

Although approved multi-agent chemotherapy regimens offer an incremental advance over single-agent treatments, the best available treatment cocktails are only marginally effective, and virtually all PDAC eventually becomes resistant to these treatments ( 1, 2 )

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(2) inhibit the expression of thioredoxin binding protein-2-a redox protein associated with diabetes that promotes apoptosis
