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Description
They work by improving local cell signaling, reducing inflammation, improving cholesterol balance, and strengthening plaque so it is less likely to rupture

One study found lower vitamin B 12 levels in the cerebrospinal fluid of patients with Alzheimer's disease than in patients with other types of dementia, though blood levels of vitamin B 12 did not differ (65)

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And retatrutide, a triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, achieved up to 24% weight loss in early trials
