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The main types of MSCs used in the treatment of DKD include adipose-derived MSCs (AD-MSCs), umbilical cord-derived MSCs (UC-MSCs), bone marrow-derived MSCs (BM-MSCs) and human urine-derived MSCs (HU-MSCs)

Effects of vascular endothelial growth factor and insulin growth factor-1 on proliferation, migration, osteogenesis and vascularization of human carious dental pulp stem cells

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2.2 Experimental design The Design Expert software (version 13, Stat-Ease Inc., Minneapolis, MN, United States) was employed to create a three-factor, three-level (3) Box-Behnken Design (BBD) with five center points, resulting in 17 experimental runs as depicted in Table 1