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Gadolinium: Actual Offender or Unwitting Pretender

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Galactorrhea occurs with: Stimulation of the afferent limb of the neuroendocrine arc Decreased dopamine release or transport or binding Autonomous prolactin secretion Hypothyroidism Chronic renal failure Hyperprolactinemia may cause anovulation through: A reduction in granulosa cell number and FSH binding Inhibition of granulosa cell 17P estradiol production by interfering with FSH action Inadequate luteinization and reduced progesterone The suppressive effects of prolactin on GnRH pulsatile release
