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on cynomolgus monkeys (25 males and 25 females, aged 35 years) utilizing rotigotine behenate-loaded PLGA microspheres (rotigotine loading of 56.256.7%) as a long-acting dopamine agonist formulation for the treatment of PD through continuous dopaminergic stimulation 138

644 Interestingly, the mRNA expression of ZnT8, a transporter closely tied to insulin secretion and hence diabetic conditions, displayed considerable variability

doi: 10.1111/j.1346-8138.2004.tb00565.x

Oral delivery of puerarin nanocrystals to improve brain accumulation and anti-Parkinsonian efficacy
